| Profhilo |
Improved skin hydration, glow & firmness, especially with early‑moderate signs of ageing.Those who don’t want volume or dramatic changes, just better texture/elasticity. |
Only ingredient is hyaluronic acid.Good “bi‑remodelling” — improves hydration, firmness & elasticity.Minimal injection points (BAP technique), relatively low downtime.Natural look, focused on skin quality. |
Mild swelling & bruising possible but low risk.Bumps visible for 24‑48 hrs post treatment.May not address deeper volume loss.Two sessions needed initially. |
2 sessions, 4 weeks apartThen 3‑4 monthly maintenance |
£370 initially(2 sessions)Then £200 maintenance |
| Profhilo Structura |
Mid‑face volume loss (ageing cheeks, hollows), natural lift/contouring without classic fillers.Excellent for weight loss patients.Sagging due to fat repositioning or loss.More structural than Profhilo but less dramatic than dermal fillers. |
Only ingredient is hyaluronic acid.Targets superficial fat pads — restoring and repositioning facial fat to give lift.Lipolifting effect, more structure support/contouring.Lasting benefit (up to 9 months).Glow without significantly altering facial volume. |
Swelling, bumps and contour irregularities temporarily.Possibly more downtime (swelling, bruising etc) for 24‑48 hours.2 sessions needed initially.Uses a cannula (some patients dislike sensation). |
Combination protocol with Profhilo2 sessions, 4 weeks apartThen every 3‑4 months |
Age 30+ £570Age 40+ £670Age 50+ £770Then £200 maintenance |
| Skinviveby Juvéderm |
Overall glow, hydration, fine line & pore improvement, smoother skin (especially cheeks).Those who don’t want fillers or altered contours, just better skin quality.Minimal downtime / lower risk. |
Glow without altering facial volume.Single session only.Only ingredient is hyaluronic acid. Vegan.Minimal downtime; mild redness/swelling that resolves.Good for fine lines, dryness, dull skin, rough texture. |
Lots of injection points.Risk of bumps/lumps (especially with microdroplets).Results are subtle; not for major laxity, hollows or pronounced volume loss. |
Single session6‑9 monthly |
£500(for 2 syringes) |
| PolynucleotidesPlinest |
Compromised skin: sun damage, scarring, thinning skin, dark/crepey eyes, inflammation/redness/rosacea.Deeper regeneration rather than just hydration.Mid‑age or older, or those wanting to enhance healing in delicate areas (under eyes, after other treatments). |
Stimulates skin regeneration & healing (fibroblasts, collagen & elastin, reducing inflammation).Good for damaged skin (sun damage, redness, scars, under‑eyes).Longer lasting structural improvements than HA alone.Minimal downtime; generally well tolerated. |
DNA derived from salmon (nb vegan/vegetarian patients).Slower onset of visible effects than HA hydration boosters.Multiple sessions required initially. |
3 sessions, 2‑3 weeks apartThen 6 monthly maintenance |
£650 initiallyThen £200 maintenance |
| NCTF 135HA |
Skin “revival” rather than lift; glow, nutrition, prevention.Dehydrated or dull skin, mild ageing signs.Good adjunct to other treatments. |
Over 60 ingredients inc. HA + vitamins, antioxidants, amino acids — “cocktail” effect: hydration + nourishment.Good skin glow, improved texture, some firmness.Can combine with botox for ‘microtox’ skin smoothing.Lots of clinical data, well established product.Can complement other treatments. |
Very superficial (but painfree Nanopass needle) so can be visible for 24‑48 hours.Lots of small injections.Multiple sessions required initially. |
3 sessions, 2‑3 weeks apartThen 3‑6 monthly |
£550 NCTF only£650 ‘microtox’Maint: £200 NCTF / £250 microtox |
| EXO|EPlant derived exosomes |
Needle phobic patients, or those interested in long term investment in skin health.Great to combine with other treatments to reduce recovery time. |
Plant based, suitable for all. Single session.Topical application only — needle free!Daily pre & post treatment serum for at‑home use.Minimal to zero downtime. |
Less published data than some options (newer product).Very gradual effect, no immediate ‘wow’ moment after treatment. |
Single session6‑9 monthly |
£450(inc pre & post serums)Serums also sold separately. |
| PurasomesBovine colostrum exosomes + microneedling |
Those whose skin is more damaged, or want more regenerative products.Moderate skin ageing; texture/scarring/pores/tone rather than sagging or volume loss. |
Regenerative effect (growth factors, ECM proteins) enhancing microneedling results.Possibly stronger cell signalling/repair vs just HA.Helps with deeper damage or skin needing more than hydration. |
Bovine source (nb vegan/vegetarian patients).Not suitable for those with cow milk allergy.Redness & downtime from microneedling (24‑48 hrs depending on depth & skin).Skin can be sensitive for a few days after.Multiple sessions needed initially. |
3 sessions, 2‑4 weeks apartThen 3‑6 monthly |
£800 initial (3 sessions)Then £275 maintenance |
| Sunekos |
A powerful, versatile vegan friendly injectable for mild to moderate concerns: dullness, crepeness, uneven texture, under eye darkness. |
Contains hyaluronic acid and amino acids to regenerate the skin.Liquid (not gel) so bumps settle relatively quicker.Good for hydration and firmness.Can have just an eye protocol. |
Occasionally mild, temporary redness & itching at injection sites.Lots of injections. |
3 sessions (2 for eyes), 2‑3 weeks apartThen 6 monthly |
£650 face£500 neck · £350 eyesThen £200 maintenance |